In message
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steveeh131047 writes
Running ladder line the whole way is the least lossy
vs mixing ladder line with coax, choke, etc..

Often, but not always:

* Depending on the impedances, frequencies and lengths involved, the
loss in a coax section can be lower than in the equivalent length of
ladderline.
* Although there may be losses in a 1:1 current balun at the
ladderline/coax transition, don't forget that there will also be
losses in the tuner balun if ladderline is used all the way; if the
ubiquitous 4:1 tuner internal voltage balun is used, those losses
could be significant.

Maybe, instead of 'ubiquitous', read 'inappropriate' (at least on
certain occasions). I'm sure that, if you can't resist the urge to use
coax, a current balun / longitudinal choke (often wound from the coax)
could have much less loss.
--
Ian